Greener Journal of Epidemiology and Public Health

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Greener Journal of Epidemiology and Public Health Vol. 2 (1), pp. 016-022, July 2014.

 ISSN: 2354-2381 © 2013 Authors

Research Paper

Manuscript Number: 041814192


Comparative Molluscicidal Activities of Methanolic and Crude Extracts of Jatropha curcas Leaves against Biomphalaria pfeifferi


Tariwari C.N. Angaye*1, Douye V. Zige1, Baraikio Didi2,

Nengimonyo Biobelemoye2 and Endurance A. Gbodo3


1Toxicology Research Unit, Department of Biological Sciences, Niger Delta University, Wilberforce Island, Bayelsa State, Nigeria.

2Medical Microbiology/Parasitology Unit, Department of Medical Laboratory Science, University of Calabar, Cross River State, Nigeria.

3Department of Biological Sciences, Faculty of Science, Federal University Otuoke, Bayelsa State Nigeria.


*Corresponding Author’s Email: maktarry @yahoo .com


The bioassay of the molluscicidal Activities of J. curcas leaves against Biomphalaria pfeifferi was investigated in vitro, using Crude and 70% methanolic extracts in a two- phased rapid and final screening test. The rapid screening of the crude extracts, for the minimal molluscicidal concentration (LC100), of the snails was less active (>500ppm), compared to the methanolic extracts (<500ppm). The final screening, revealed an LC50 and LC100 values of 6 and 30ppm respectively. Further investigation based on exposure, revealed a mortality within 12 hours, which meets WHO standard of less than 24 hours for a potential molluscicide. These results confirmed that J. curcas leaves can be regarded as a potential molluscicide for the control of schistosomiasis and therefore encourage the cultivation of this plant in endemic regions.

Keywords: Biomphalaria sp., Jathropha curcas, molluscicidal activities, schistosomiasis, rapid screening, final screening.


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