Oke et al
Greener Journal of Medical Sciences Vol. 3 (8), pp. 289-293, October 2013.
ISSN: 2276-7797 © 2011 Greener Journals
Manuscript Number: 052813643
Effect of Alcohol Consumption On Platelets Count, Intrinsic and Extrinsic Pathways of Blood Coagulation
Oke Olusegun Taiwo1*, Adeyanju Oluwaseyi Adeteju2,
Oyedeji Samuel Oyewole1, Adedire Olusoji Aderemi1,
Adewuyi Isaac Kayode1, Grace Oludayo3
1School of Medical Laboratory Science, Obafemi Awolowo University Teaching Hospital Complex, P.M.B.5538. Ile-Ife.
2Haematology Department, University College Hospital Ibadan
3Anesthetic Department, Obafemi Awolowo University Teaching Hospital Complex, P.M.B.5538. Ile-Ife.
*Corresponding Author’s Email: oketaiwo @ yahoo.com, Phone: +2348033772582
Alcohol is like a cankerworm that has eaten deep into the fabrics of our society. Contrary to popular belief it is not a habit, rather it is a disease. It can also be viewed as a form of drug addiction. Alcoholism is a degenerative disease that often causes long term physical, emotional and behavioral complication for the victim. Effect of alcohol on platelets count, intrinsic and extrinsic pathways of blood coagulation were determined on one hundred (100) willingly volunteered subjects. Twenty five (25) of them served as control and the remaining seventy five (75) were grouped into three, twenty five (25) in each group as heavy, moderate and occasional drinkers. The grouping was done based on the number of beer bottles they took and how regular they took it. The occasional drinkers were those that took three to four bottles of beer a week and the drinking pattern was not regular. Moderate drinkers took 5 to 7 bottles a week while the heavy drinkers took more than seven bottles per week. Estimated parameters were platelets counts, prothrombin time test and activated partial thromboplastin time test. It was observed that there were statistically significant differences (p<0.05) in all the parameters estimated in moderate and heavy drinkers, while the experimental differences seen in the parameters of occasional drinkers were not statistically significant (p>0.05).
Keywords: Platelets, Prothrombin time, Activated Partial thromboplastin time test, Alcohol, Intrinsic, Extrinsic.