Greener Journal of Medical Sciences

Open Access

Chijioke-Nwauche and Nwauche

Greener Journal of  Medical Sciences Vol. 6 (3), pp. 042-045, June 2016.

 ISSN: 2276-7797 © 2015 Greener Journals

Research Paper

Manuscript Number: 052616100



HIV Infections in Mothers and their New-born Babies in University of Port Harcourt Teaching Hospital, Port Harcourt Nigeria


Chijioke-Nwauche IN*1, Nwauche CA2


1Department of Clinical Pharmacy and Management, Faculty of Pharmaceutical Sciences, University of Port Harcourt, Port Harcourt.

2Department of Haematology and  Blood Transfusion, University of Port Harcourt Teaching Hospital, Port Harcourt.


The strategic position of Nigeria in the global map of HIV calls for continuous and progressive study of HIV and its impact in the country particularly in pregnancy because of the risk of transmission to the foetus. Treatment of infected mothers is therefore very essential because of the dangers of transmitting the disease to their babies. The study was carried out to determine the prevalence of HIV antibodies in maternal and cord blood from pregnant mothers who presented at the University of Port Harcourt Teaching Hospital, Port Harcourt for delivery of their babies. Venous blood was collected from a total of 103 mother and neonatal cord pair at delivery.  The sera were analysed by double ELISA techniques for HIV-1 and HIV-2. Eight (7.8%) out of the 103 mothers tested positive for HIV-1 and none for HIV-2. Five out of the eight mothers had antibody positivity in their babies’ cord blood, showing a transmission rate of 62.5%.  All the mothers delivered per vagina. The study shows that mother to child transmission is high in the study area compared to the WHO rate of 30%. This underlines the importance of enforcing the prevention of mother to child transmission policy among HIV-infected mothers in the environment.


Keywords: HIV, mothers, cord blood, new born babies.

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Bollinger, L., Stover. J &Nwaorgu, O.The Economic Impact of AIDS in Nigeria. The Futures Group International in collaboration with: Research Triangle Institute (RTI). The Centre for Development and Population Activities (CEDPA). 1999.


Chijioke-Nwauche I &Akani Y. Socio-demographic profile of people living with HIV/AIDS in Port Harcourt, Nigeria. The Nigerian Health Journal, 2014.Vol, 14, No 3.pp 119-125


Eneh, A.U. Human Immune Virus Infection: In: Paediatric and Child Health in aTropical Region. Editors: Azubike, J.C and Nkangineme, K.E.O. Owerri, 2nd Edition. 2007;pp 643-653.


Federal Ministry of Health.'National Blood Transfusion Service - About Us' 2009.


Federal Ministry Of Health Nigeria (FMOH). Guidelines for the use of antiretroviral (ARV) drugs in Nigeria, 2005.


NARHS Plus. National HIV/AIDS Reproductive Health Survey Plus, 2012.


Nasdi, A & Harry. T. In Nigeria: ‘A nation on threshold’ Chapter 2. The epidemiology of HIV/AIDS in Nigeria.Editors.OlusolaAdeyi, Phyllis J Kanki, OluwoleOdutolu, John A Idoko. Harvard Center for Population and Development Studies. 2006.pp 17-36.


National Agency for the Control of AIDS (NACA), Global AIDS Response Country Progress Report, 2015.


Nwauche, C. A. &Akani, C. I.An assessment of high risk sexual behaviour and HIV transmission among migrant oil workers in the Niger Delta area of Nigeria.Niger J ClinPract,2006; 9, 48-51.


UNAIDS/WHO. AIDS Epidemic update: Geneva, UNAIDS.2001


UNAIDS/AIDS Epidemic Update. Geneva. 2005.


UNAIDS/WHO, AIDS Epidemic update. 2006.




UNICEF.Prevention of mother to child transmission PMTCT.2015. March, 2015.


USAID, Risk of HIV/AIDS Transmission: Programme overview-strategic objectives. 2006.


WHO, Mother to child transmission of HIV. 2015 May, 2015