Oguwike et al
Greener Journal of Medical Sciences Vol. 7 (4), pp. 036-041, July 2017.
Manuscript Number: 061717075
The effects of Cyperus esculentus (Tiger nut) on Haematological and Biochemical Profile of Male Hypercholesteremic Subjects in Uli, Anambra State Nigeria
Oguwike F.N.*1, Eluke B.C.2, Eze R.I.3, Asika C.M.4, Nwosu P.N.1, Nwafor C.1, Onumonu C.1
1Department of Physiology, Faculty of Basic Medical Sciences. Chukwuemeka Odumegwu Ojukwu University Uli Campus, Anambra state.
2Department of Medical Lab. Sciences, Faculty of Health Sciences University of Nigeria Enugu Campus.
3Department of Medical Lab. Sciences, Madonna University Elele Rivers State.
4Department of Pharmacology, Ebonyi state University Ebonyi state.
Cholesterol, though needful in the body, when it is excess in the body can build up in the coronary arteries and increase the risk of heart diseases. This provoked our enthusiasm to research on plant material or nut that when eaten can knock down high cholesterol in the body.
Tiger nut is one of such nuts. It is called “Aya’’ in Hausa “Ofio’’ in Yoruba, and “Akiausa’’ in Igbo. It contains high level of oleic acid which has the potentials to exert a negative effect on cholesterol present in the human blood. This encouraged the study using Tiger nut. 80 persons consisting of both male and female adults diagnosed of high cholesterol were randomly selected for this study.
They were placed on the ingestion of tiger nut along with their normal diets for 14days. At the end of 28 days, blood samples were collected from them before and after the ingestion of tiger nut for biochemical and haematological analysis.
Results of the analysis indicate that tiger nut did not have any effect on the haemoglobin concentrations, packed cell volume, white blood cell count, platelet count and liver function profiles,but it drastically reduced the cholesterol level of the subjects. It could be deduced from the study that tiger nut contains some active principles that can lower cholesterol levels in the subjects.
Keywords: cholesterol, Tiger nut, venous blood, Haemoglobin, Packed cell volume, Platelets, White blood cell count.
Akuoma O, Elekwa U.A, Afodunrinbi A.T and Onyeukwa G.C (2000). Yogurt from coconut and Tiger nut. TJFD Tech. Africa 5:132-134.
Alexander R.R and Griffit J.N (1993). Haematocrit in Basic Biochemical methods 2nd edition. John Willey and sons inc. publications, Newyork Pp 186-187.
Baker F.J, Silverton R.E, Pallister C.J (1998). Renal function tests. Baker and Silvertons. Introduction to medical Laboratory Technology. Published by Butterworths and Heinenmann, Linacre House, Jordan Hill, Oxford Ox2 8DP p 140-150
Bamgbose A.M, Truvbetine D and Dada W (2003). Utilization of Tiger nut (Cyperus totundus L) meal in the drits for cockerel starters. Biones. Tech 89: 245-248.
Dacie J.K and Lewis S.M (1991). Practical haematology. Published in London. Churchhill Living Stone Pp 186-187
Harbourne J.B.C (1973). Phytochemical method. Chapman and Hall, London p 269.
Hu F.B, Atampfor M.J (1999). Nut consumption and risk of coronary heart disease, a review of epidemologic evidence. Curr. Artheroder Rep 1999, 1204-9 (Pubmed).
Lorke D, 1983: A new approach to practical acute toxicity testing. Arc. Toxicology 54 : 275-278.
Trease G.E and Evans W.C (1996): Textbook of Pharmcognosy, 14th Ed, W.B Saunders, London p11
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