Microbial Load and Resistance Pattern of Bacteria Organisms in the Gastrointestinal Tract of Household Rat

Background: Household rats are known agents of human diseases worldwide. They are vehicles of transmission of bacteria, viral, fungal, and protozoal disease to man. Rats and human guts with similarities are colonized with normal flora that can harbor multidrug-resistant organisms transmissible to man. Aim: This study investigates the microbial load of household rats and their resistance micro-organisms which are transmissible to man. This knowledge is useful for household rat disease burden management in our environment and the healthcare setting. Method: This was cross-sectional descriptive and analysis of 200 trapped rats collected from 100 households in Abraka, Nigeria after consent were obtained Results: The results from the study shows more bacteria load in the small intestine of household rats compared to the throat and large intestines. Bacteriodes fragilis and Escherichia coli were the predominant bacteria obtained, while Candida albicans and other Candida species were the most abundant fungi seen. More than two-thirds of the bacteria isolates were resistant to commonly used antibiotics such as Ampicillin, Penicillin, Trimetoprin-Sulphamethoxazole, and Ceftriaxone. Conclusion: Households rats in our study indicate a high bacteria and fungi load burden with increased bacteria resistance. Reporting this zoonotic disease associated with these organisms, proper diagnosis and management are required to mitigate this potential source burden of disease-causing agents. Read more
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Microbial Load and Resistance Pattern of Bacteria Organisms in the Gastrointestinal Tract of Household Rat

Background: Household rats are known agents of human diseases worldwide. They are vehicles of transmission of bacteria, viral, fungal, and protozoal disease to man. Rats and human guts with similarities are colonized with normal flora that can harbor multidrug-resistant organisms transmissible to man. Aim: This study investigates the microbial load of household rats and their resistance micro-organisms which are transmissible to man. This knowledge is useful for household rat disease burden management in our environment and the healthcare setting. Method: This was cross-sectional descriptive and analysis of 200 trapped rats collected from 100 households in Abraka, Nigeria after consent were obtained Results: The results from the study shows more bacteria load in the small intestine of household rats compared to the throat and large intestines. Bacteriodes fragilis and Escherichia coli were the predominant bacteria obtained, while Candida albicans and other Candida species were the most abundant fungi seen. More than two-thirds of the bacteria isolates were resistant to commonly used antibiotics such as Ampicillin, Penicillin, Trimetoprin-Sulphamethoxazole, and Ceftriaxone. Conclusion: Households rats in our study indicate a high bacteria and fungi load burden with increased bacteria resistance. Reporting this zoonotic disease associated with these organisms, proper diagnosis and management are required to mitigate this potential source burden of disease-causing agents. Read more
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Microbial Load and Resistance Pattern of Bacteria Organisms in the Gastrointestinal Tract of Household Rat

Background: Household rats are known agents of human diseases worldwide. They are vehicles of transmission of bacteria, viral, fungal, and protozoal disease to man. Rats and human guts with similarities are colonized with normal flora that can harbor multidrug-resistant organisms transmissible to man. Aim: This study investigates the microbial load of household rats and their resistance micro-organisms which are transmissible to man. This knowledge is useful for household rat disease burden management in our environment and the healthcare setting. Method: This was cross-sectional descriptive and analysis of 200 trapped rats collected from 100 households in Abraka, Nigeria after consent were obtained Results: The results from the study shows more bacteria load in the small intestine of household rats compared to the throat and large intestines. Bacteriodes fragilis and Escherichia coli were the predominant bacteria obtained, while Candida albicans and other Candida species were the most abundant fungi seen. More than two-thirds of the bacteria isolates were resistant to commonly used antibiotics such as Ampicillin, Penicillin, Trimetoprin-Sulphamethoxazole, and Ceftriaxone. Conclusion: Households rats in our study indicate a high bacteria and fungi load burden with increased bacteria resistance. Reporting this zoonotic disease associated with these organisms, proper diagnosis and management are required to mitigate this potential source burden of disease-causing agents. Read more
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Microbial Load and Resistance Pattern of Bacteria Organisms in the Gastrointestinal Tract of Household Rat

Background: Household rats are known agents of human diseases worldwide. They are vehicles of transmission of bacteria, viral, fungal, and protozoal disease to man. Rats and human guts with similarities are colonized with normal flora that can harbor multidrug-resistant organisms transmissible to man. Aim: This study investigates the microbial load of household rats and their resistance micro-organisms which are transmissible to man. This knowledge is useful for household rat disease burden management in our environment and the healthcare setting. Method: This was cross-sectional descriptive and analysis of 200 trapped rats collected from 100 households in Abraka, Nigeria after consent were obtained Results: The results from the study shows more bacteria load in the small intestine of household rats compared to the throat and large intestines. Bacteriodes fragilis and Escherichia coli were the predominant bacteria obtained, while Candida albicans and other Candida species were the most abundant fungi seen. More than two-thirds of the bacteria isolates were resistant to commonly used antibiotics such as Ampicillin, Penicillin, Trimetoprin-Sulphamethoxazole, and Ceftriaxone. Conclusion: Households rats in our study indicate a high bacteria and fungi load burden with increased bacteria resistance. Reporting this zoonotic disease associated with these organisms, proper diagnosis and management are required to mitigate this potential source burden of disease-causing agents. Read more
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