Seroprevalence of Chlamydia trachomatis Antibodies and Associated Risk Factors Among HIV Positive Patients Seen in Enugu

A cross-sectional study of Chlamydia trachomatis antibody seroprevalence was carried out among persons living with HIV in Enugu, Nigeria. One hundred and fifty persons diagnosed of HIV and receiving treatment at the University of Nigeria Teaching Hospital, Enugu were recruited for the study. Enzyme-linked immunosorbent assay kits were used to assess the seroprevalence of Chlamydia trachomatis antibodies among the participants. A structured PROFORMA was used to collect data on demographic factors and high-risk behaviours. The results showed a 60.7% (91/150) of Chlamydia trachomatis antibodies among the study participants. Among the participants with antibodies, the IgM prevalence was 51.6% (47/91), while IgG was 35.2% (32/91) and both IgM and IgG were 13.2% (12/91). Logistic regression showed that the risk of chlamydia infection was increased with the history of STD (OR = 1.4, (0.7 – 2.7)), history of multiple sexual partners (OR = 1.9, (0.9 – 3.7)), those currently sexually active (OR = 1.5, (0.7 – 3.1)), the use of unsterilized objects (OR = 4.9, (2.3 – 10.4)) and the irregular or non-usage of condoms (OR = 10.2 (4.6 – 22.7)). The findings of the study showed a high prevalence of C. trachomatis antibodies among the participants. Although these may not all represent active C. trachomatis infection, it can be inferred that a high percentage of the population has been exposed to the infection and many of them may still be harbouring this infection inadvertently. This may contribute to the high rate of spread of this infection as well as HIV in Nigeria. Read more
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Seroprevalence of Chlamydia trachomatis Antibodies and Associated Risk Factors Among HIV Positive Patients Seen in Enugu

A cross-sectional study of Chlamydia trachomatis antibody seroprevalence was carried out among persons living with HIV in Enugu, Nigeria. One hundred and fifty persons diagnosed of HIV and receiving treatment at the University of Nigeria Teaching Hospital, Enugu were recruited for the study. Enzyme-linked immunosorbent assay kits were used to assess the seroprevalence of Chlamydia trachomatis antibodies among the participants. A structured PROFORMA was used to collect data on demographic factors and high-risk behaviours. The results showed a 60.7% (91/150) of Chlamydia trachomatis antibodies among the study participants. Among the participants with antibodies, the IgM prevalence was 51.6% (47/91), while IgG was 35.2% (32/91) and both IgM and IgG were 13.2% (12/91). Logistic regression showed that the risk of chlamydia infection was increased with the history of STD (OR = 1.4, (0.7 – 2.7)), history of multiple sexual partners (OR = 1.9, (0.9 – 3.7)), those currently sexually active (OR = 1.5, (0.7 – 3.1)), the use of unsterilized objects (OR = 4.9, (2.3 – 10.4)) and the irregular or non-usage of condoms (OR = 10.2 (4.6 – 22.7)). The findings of the study showed a high prevalence of C. trachomatis antibodies among the participants. Although these may not all represent active C. trachomatis infection, it can be inferred that a high percentage of the population has been exposed to the infection and many of them may still be harbouring this infection inadvertently. This may contribute to the high rate of spread of this infection as well as HIV in Nigeria. Read more
Read More

Seroprevalence of Chlamydia trachomatis Antibodies and Associated Risk Factors Among HIV Positive Patients Seen in Enugu

A cross-sectional study of Chlamydia trachomatis antibody seroprevalence was carried out among persons living with HIV in Enugu, Nigeria. One hundred and fifty persons diagnosed of HIV and receiving treatment at the University of Nigeria Teaching Hospital, Enugu were recruited for the study. Enzyme-linked immunosorbent assay kits were used to assess the seroprevalence of Chlamydia trachomatis antibodies among the participants. A structured PROFORMA was used to collect data on demographic factors and high-risk behaviours. The results showed a 60.7% (91/150) of Chlamydia trachomatis antibodies among the study participants. Among the participants with antibodies, the IgM prevalence was 51.6% (47/91), while IgG was 35.2% (32/91) and both IgM and IgG were 13.2% (12/91). Logistic regression showed that the risk of chlamydia infection was increased with the history of STD (OR = 1.4, (0.7 – 2.7)), history of multiple sexual partners (OR = 1.9, (0.9 – 3.7)), those currently sexually active (OR = 1.5, (0.7 – 3.1)), the use of unsterilized objects (OR = 4.9, (2.3 – 10.4)) and the irregular or non-usage of condoms (OR = 10.2 (4.6 – 22.7)). The findings of the study showed a high prevalence of C. trachomatis antibodies among the participants. Although these may not all represent active C. trachomatis infection, it can be inferred that a high percentage of the population has been exposed to the infection and many of them may still be harbouring this infection inadvertently. This may contribute to the high rate of spread of this infection as well as HIV in Nigeria. Read more
Read More

Seroprevalence of Chlamydia trachomatis Antibodies and Associated Risk Factors Among HIV Positive Patients Seen in Enugu

A cross-sectional study of Chlamydia trachomatis antibody seroprevalence was carried out among persons living with HIV in Enugu, Nigeria. One hundred and fifty persons diagnosed of HIV and receiving treatment at the University of Nigeria Teaching Hospital, Enugu were recruited for the study. Enzyme-linked immunosorbent assay kits were used to assess the seroprevalence of Chlamydia trachomatis antibodies among the participants. A structured PROFORMA was used to collect data on demographic factors and high-risk behaviours. The results showed a 60.7% (91/150) of Chlamydia trachomatis antibodies among the study participants. Among the participants with antibodies, the IgM prevalence was 51.6% (47/91), while IgG was 35.2% (32/91) and both IgM and IgG were 13.2% (12/91). Logistic regression showed that the risk of chlamydia infection was increased with the history of STD (OR = 1.4, (0.7 – 2.7)), history of multiple sexual partners (OR = 1.9, (0.9 – 3.7)), those currently sexually active (OR = 1.5, (0.7 – 3.1)), the use of unsterilized objects (OR = 4.9, (2.3 – 10.4)) and the irregular or non-usage of condoms (OR = 10.2 (4.6 – 22.7)). The findings of the study showed a high prevalence of C. trachomatis antibodies among the participants. Although these may not all represent active C. trachomatis infection, it can be inferred that a high percentage of the population has been exposed to the infection and many of them may still be harbouring this infection inadvertently. This may contribute to the high rate of spread of this infection as well as HIV in Nigeria. Read more
Read More