Vol. 11(2), pp. 109-112 2021
ISSN: 2276-7797
Copyright ©2021, the copyright of this article is retained by the author(s)
https://gjournals.org/GJMS
Effect of Hydroalcohol Extract of Englerina drummondii Balle ex Polhill & Wiens (Mistletoe) Leaves on Prolactin and Thyroid Stimulating Hormone (TSH) in Female Wistar Rats.
1*Gbaranor K. B., 2Ovili-Odili B. Z., 1Okpara E. P. 1Tamuno-Opubo A., 3Victor P. D., 3Orupabo C. D., 1Tee P. G., 4Alasia O. M.,5Sapira-Ordu L 1Nonju I. I., 6Nwosu G. N.
1Department of Human Physiology, College of Medical Sciences, Rivers State University, Port Harcourt, Nigeria.
2Department of Human Physiology, College of Health Sciences, University of Port Harcourt, Nigeria.
3Department of Human Anatomy, College of Medical Sciences, Rivers State University, Port Harcourt, Nigeria.
4Department of Pharmacology, College of Medical Sciences, Niger Delta University, Bayelsa State, Nigeria.
5Department of Obstetrics and Gynaecology, Rivers State University Teaching Hospital, Port Harcourt, Nigeria
6Department of Paediatrics, Rivers State University Teaching Hospital, Port Harcourt, Nigeria
Article No.: 080821076
Type: Research
Phytomedicine is a branch of medicine that is practice across the globe and can not be underrate. It is a branch of medicine that specialize in treating patients with plant materials such as the roots, leaves, fruits, flowers and bark. The aim of this study is to investigate effects of hydroalcohol extract of Englerina drummondii Balle ex Polhill & Wiens (mistletoe) leaves from avocado trees on prolactin and thyroid stimulating hormone (TSH) in female wistar rats. Twenty female wistar rats weighing between 160g to 180g were used for this study. The animals were divided into 4 groups, with five (5) rats per group. Group 1 (control) were administered 5ml/kg of distil water, group 2 received extract 100mg/kg, group 3 extract 200mg/kg, and group 4 extract 400mg/kg. The distil water and extract were administered through gavage at 08.00 hour once daily for 28 days. Our study revealed significant increase in prolactin (0.69 ± 0.01*) when extract of 100mg/kg was administered and significantly decreased in prolactin (0.23 ± 0.01) when extract of 400mg/kg was administered to the animals. Thyroid stimulating hormone (TSH) significantly decreased when 100mg/kg of extract (0.24 ± 0.01) was given and significantly increased when extract doses of 200mg/kg (0.78 ± 0.05) and 400mg/kg (0.80 ± 0.03) was administered respectively. Statistical analysis was done using SPSS version 24 and ANOVA, p < 0.05 was significant.
Accepted: 16/08/2021
Published: 31/08/2021
*Corresponding Author
Gbaranor Kekii Barinua
E-mail: barinua.gbaranor@ ust.edu.ng
Phone: +2348037414186
Keywords:
Effect; Hydroalcohol; Avocado trees; Prolactin; Thyroid Stimulating Hormone.
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Journal Name : citation_journal : Greener Journal of Medical Sciences
